When checking the result of "cnvkit.py genemetrics", I found the algorithm consider a downstream antitarget bin when merging bins for each gene. I wonder if it is a bug or there are some reasons for it.
e.g.
a part of the input cnr file:
the output of genemetrics:
The merged "BCL2L11" gene includes an antitarget bin from chr2 111888253 to 112037344.
Hi @etal and everyone,
When checking the result of "cnvkit.py genemetrics", I found the algorithm consider a downstream antitarget bin when merging bins for each gene. I wonder if it is a bug or there are some reasons for it.
e.g. a part of the input cnr file:
the output of genemetrics:
The merged "BCL2L11" gene includes an antitarget bin from chr2 111888253 to 112037344.
version: 0.9.10 command line: cnvkit.py genemetrics -m 0 -t 0 ${copyratio_cnr} -o ${genemetrics_cns}
Bw, Leon