etal / cnvkit

Copy number variant detection from targeted DNA sequencing
http://cnvkit.readthedocs.org
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Using CNVkit with THetA2 and "Sample_paired.vcf"? #882

Open ngs-seqer opened 4 months ago

ngs-seqer commented 4 months ago

Hi,

I use the pooled and not-matched normal samples to run cnvkit and now I want to create interval_count, tumor.snp_formatted.txt and *normal.snp_formatted.txt to run THetA2.

I found this example in your manual:

cnvkit.py export theta Sample_T.cns reference.cnn -v Sample_Paired.vcf

I can locate *cns and reference.cnn files generated from the CNVkit-batch mode, but where is this "Sample-Paired.vcf"? or How can I generate this vcf file?

Could you provide some example codes showing how to get this vcf file?