[TERM] Inner exposure surface

[clementblassiau]

It seems to me that the term 'inner exposure surface' is used in a different sense from the definition.

In the AD6.3 glossary, the following definitions were proposed:

Exposure surface. [adapted from (IPCS and IOMC 2004)]. A surface on a target where a substance is present. A distinction could be made between the surfaces inside the body, i.e. inner exposure surfaces, and those outside the body, i.e. outer exposure surfaces, that have in common to be located before an absorption barrier. Examples of outer exposure surfaces include the exterior of an eyeball, the skin surface, and a conceptual surface over the nose and open mouth. Examples of inner exposure surfaces include the gastrointestinal tract, the respiratory tract, and the urinary tract lining.

Internal exposure. [adapted from (US EPA et al. 2008); and (IPCS and IOMC 2004)]. The amount of substance that passes through an absorption barrier and reaches a targeted biological matrix. These include, for example, exposure of urine, blood, or even of specific organs.

---> According to this definition, inner exposure surface is a possible site of external exposure (before an absorption barrier). The site of internal exposure (after an absorption barrier) could be called a 'targeted biological matrix'.

[jwkruisselbrink]

Action point meeting (31/8): Clement and David to propose improved schema as picture (in this issue).

[clementblassiau]

Proposal of improvement done, in relation to the previous comment. Commit 6898bcab54fd9fbd261f441ea2fa59f383507ba3 to commit 058c9fa4357ea6a6ad4ce30726c8a5472c9aeb7b.

Previous diagram :

New proposal :