add substances after X hours

[fairquestion]

Dear all,

I was wondering if it is possible to add substances to the arena during the simulation. For example after 10 hours in a simulation of 20 hours. Do you have any idea about this?

Thanks in advance, fair

[euba]

Hi,

Yes, this should be possible. You just need to start the simulation, interupt it and take the last simulation arena object, add the additional concentration, and then simulate the modified arena object again like here:

data("Ec_core")
bac <- Bac(Ec_core)
arena <- Arena(n=20, m=20)
arena <- addOrg(arena,bac,amount=1)
arena <- addSubs(arena, smax=0.01, unit="mM")
sim <- simEnv(arena,time=10)

arena2 <- getArena(sim,10) #take the last simulation step
arena2 <- addSubs(arena2, smax=0.01, unit="mM", add=T)
sim2 <- simEnv(arena2,time=10)
plotCurves(sim)
plotCurves(sim2)

Cheers, Eugen

[jotech]

I think the solution proposed by @euba is the easiest solution! Another would be to define a custom diffusion problem with influx for the boundaries conditions.

[fairquestion]

Hi all!

Yes, it works!

Thanks a lot, Fair