Open damiansm opened 6 years ago
We'd need more information about the patient in order to do this. Something like a phenopacket would fit the bill. Assuming age of onset of each phenotype term is provided it would also allow for much more accurate disease diagnosis.
Requires #373
Will also need changes to :
[ ] disease_hp table schema,
[ ] disease DAO
[ ] disease model
[ ] update to Sample
to include Age
/Onset
, PhenotypicFeature
[ ] signature change to Prioritiser
to accept a Sample
.
[ ] update to HiPhive logic to filter out mismatched diseases for a patient
Should we somehow have a disease-level age of onset filter one day i.e. if we know the genome is from a newborn don't highlight a phenotype match based on Parkinson's disease etc!
Slightly less silly versions of this are sometimes the reason the clinicians reject an Exomiser candidate when I present it to them and would be cool to automate somehow