This will align the input data better with the contents of a phenopacket. Having these fields outside of the pedigree will also enable correct assignment of X-linked variants in males where the caller returns a 0/1 genotype instead of 1/1 for hemizygous alleles.
Having an age will enable better accuracy when scoring against late/early onset diseases as mentioned in #254
Tangentially related to #330 where we're trying to improve MOI matching to disease as opposed to age of onset matching.
This will align the input data better with the contents of a phenopacket. Having these fields outside of the pedigree will also enable correct assignment of X-linked variants in males where the caller returns a 0/1 genotype instead of 1/1 for hemizygous alleles.
Having an age will enable better accuracy when scoring against late/early onset diseases as mentioned in #254
Tangentially related to #330 where we're trying to improve MOI matching to disease as opposed to age of onset matching.