Detecting Indicators of Inflammatory Response
It is recommended to conduct tests of C-reactive protein, procalcitonin, ferritin,
D-dimer, total and subpopulations of lymphocytes, IL-4, IL-6, IL-10, TNF-α, INF-γ and
other indicators of inflammation and immune status, which can help evaluate clinical
progress, alert severe and critical tendencies, and provide a basis for the formulation of
treatment strategies.
Most patients with COVID-19 have a normal level of procalcitonin with significantly
increased levels of C-reactive protein. A rapid and significantly elevated C-reactive
protein level indicates a possibility of secondary infection. D-dimer levels are
significantly elevated in severe cases, which is a potential risk factor for poor prognosis.
Patients with a low total number of lymphocytes at the beginning of the disease
generally have a poor prognosis. Severe patients have a progressively decreased
number of peripheral blood lymphocytes. The expression levels of IL-6 and IL-10 in
severe patients are increased greatly. Monitoring the levels of IL-6 and IL-10 is helpful to
assess the risk of progression to a severe condition.
Detecting Indicators of Inflammatory Response It is recommended to conduct tests of C-reactive protein, procalcitonin, ferritin, D-dimer, total and subpopulations of lymphocytes, IL-4, IL-6, IL-10, TNF-α, INF-γ and other indicators of inflammation and immune status, which can help evaluate clinical progress, alert severe and critical tendencies, and provide a basis for the formulation of treatment strategies. Most patients with COVID-19 have a normal level of procalcitonin with significantly increased levels of C-reactive protein. A rapid and significantly elevated C-reactive protein level indicates a possibility of secondary infection. D-dimer levels are significantly elevated in severe cases, which is a potential risk factor for poor prognosis. Patients with a low total number of lymphocytes at the beginning of the disease generally have a poor prognosis. Severe patients have a progressively decreased number of peripheral blood lymphocytes. The expression levels of IL-6 and IL-10 in severe patients are increased greatly. Monitoring the levels of IL-6 and IL-10 is helpful to assess the risk of progression to a severe condition.