MY "LONG COVID PROTOCOL" - 3
(TREATMENT STRATEGIES)
after 30 days, inflammatory mediators are subsided
anatomical/physiological insults to organs is persisting
organ specific injuries are treated accordingly (irrespective of original disease process)
1/1
PREGABALINE/NORTRIPTYLINE
*CITICOLINE
yes dear, my take is that these are reversible. even in 6-7 months old cases, 90% recovery is expected. just treat it like diabetic neuropathy.
long haulers are neurological symptoms, equivalent to toxic/metabolic neuropathy
rarely, delayed/poorly treated, may be irreversible
PULSE THERAPY IN COVID DISEASE?
acute viral phase
i recommend an antiviral treatment, 10-14 days
using pulse therapy, one week each
*PULSE 1- HCQ+AZM+FEVIPIRAVIR
2- IVM+DOXY+ARTEMISIN
DIPYRIDAMOLE AND PENTOXYPHYLLINE
petoxyphylline is still my favourite, but now a day nobody use it so not available easily.
next to dipyridamole, it was my second choice in covid.
post covid syndrome
POST COVID SYNDROME
basic problems, manifesting in symptomatologies
HYPOXIA AND RESPIRATORY DISTRESS
SEROTONIN OVERACTIVITY/SYNDROME
BRADYKININ/CYTOKIN STORM
HEPATIC DYSFUNCTIONS
AUTONOMIC NERVOUS SYSTEM INSTABILITY
NEURO-TRANSMITTERS/HORMONES IMBALENCE
mytakeoncovid19
ischemia leading to oedema, the proteins present in exudates are potent stimulus to fibrotic process.
keeping oedema and exudates to minimum by any means, prevents/delays the fibrosis.
this was the basic reasoning, my opinion that fibrosis is 100% preventable, if managed early.
antithrombotics are always helpful, since thrombotic pathology in pulmonary fibrosis is inevitable. magnitude may be different.
the easiest pathology to manage is inflammatory oedema leading to pulmonary fibrosis, reducing much of the fibrotic load.
PROLONGED HYPOXIA TO CNS, IN COVID
causes, ischaemic, toxic and metabolic injuries
magnitude of injury depends on duration of hypoxia and levels of inflammation
persistence of neural insults may be short term, long term or permanent
our treatment must be directed to,
1/1
SIGMA AGONISTS FOR POTENTIAL USE IN SARS-COV2
commonly used and available compounds known to possess sigma agonist activity,
FLUVOXAMINE
FLUOXETINE
OPIPRAMOL
BERBERINE
SEROTONIN EXESS
IN BRAIN CAUSES, SEROTONIN SYNDROME
IN BLOOD CSUSES, ENDOTHELIAL DYSFUNCTION, THROMBOSIS AND MULTIPLE ORGAN FAILURE
both are grossly different. one cause neurological dysfunction, other causes organ dysfunction.
after demonization of hcq and ivm,
just shifting to,
NITAZOXANIDE
FLUVOXAMINE
NICLOSAMIDE
MEFLOQUINE
all are presumably available everywhere and a witty doc can use it to save his pts.
"SPIROLOLACTONE
spironolactone is big hope in treating post covid syndrome
it has proved extremely effective in treating covid hypoxia(cutting down illness to about 2 weeks)
*my last 2 months pt's feedbacks give me confidence of it's efficacy in post covid syndrome"
28 sept 20 https://t.co/rXiuYNczMV
PROPHYLAXIS PROTOCOL FOR COVID19
IVERMECTIN 12mg /weekly for 6-8 weeks
TAB HCQS-400 mg /weekly for 6-8 weeks
(this is dose for prophylaxis)
the sample formulation for a post covid case (long houler),
with POTS,
TAB CITICOLIN-500 1 tab once daily
TAB CLONAZEPAM .25mg 1 tab once daily
TAB MODAFINIL-100 1 tab daily(in morning)
TAB CEREVATE 1 tab once daily
Dr Chaurasia
Acute covid
ACUTE COVID, FIRST LINE TREATMENT SCEDULE
HCQ+FAVIPIRAVIR+AMBROX-NAC+ACECLO-PARA-BROM+RABEPRAZOL+CEFIXIM-CLAV
prophylaxis
long covid
gastrointestinal
neurological
MY "LONG COVID PROTOCOL" DRUGS - 2 (neurological)
https://twitter.com/drakchaurasia/status/1317869216947523585?s=19
MY "LONG COVID PROTOCOL" - 3 (TREATMENT STRATEGIES)
after 30 days, inflammatory mediators are subsided anatomical/physiological insults to organs is persisting organ specific injuries are treated accordingly (irrespective of original disease process) 1/1 PREGABALINE/NORTRIPTYLINE *CITICOLINE
yes dear, my take is that these are reversible. even in 6-7 months old cases, 90% recovery is expected. just treat it like diabetic neuropathy.
long haulers are neurological symptoms, equivalent to toxic/metabolic neuropathy rarely, delayed/poorly treated, may be irreversible
PULSE THERAPY IN COVID DISEASE? acute viral phase
i recommend an antiviral treatment, 10-14 days using pulse therapy, one week each *PULSE 1- HCQ+AZM+FEVIPIRAVIR 2- IVM+DOXY+ARTEMISIN
DIPYRIDAMOLE AND PENTOXYPHYLLINE petoxyphylline is still my favourite, but now a day nobody use it so not available easily. next to dipyridamole, it was my second choice in covid.
post covid syndrome
POST COVID SYNDROME basic problems, manifesting in symptomatologies
HYPOXIA AND RESPIRATORY DISTRESS SEROTONIN OVERACTIVITY/SYNDROME BRADYKININ/CYTOKIN STORM HEPATIC DYSFUNCTIONS AUTONOMIC NERVOUS SYSTEM INSTABILITY NEURO-TRANSMITTERS/HORMONES IMBALENCE
mytakeoncovid19
ischemia leading to oedema, the proteins present in exudates are potent stimulus to fibrotic process.
keeping oedema and exudates to minimum by any means, prevents/delays the fibrosis. this was the basic reasoning, my opinion that fibrosis is 100% preventable, if managed early.
antithrombotics are always helpful, since thrombotic pathology in pulmonary fibrosis is inevitable. magnitude may be different.
the easiest pathology to manage is inflammatory oedema leading to pulmonary fibrosis, reducing much of the fibrotic load.
PROLONGED HYPOXIA TO CNS, IN COVID
causes, ischaemic, toxic and metabolic injuries magnitude of injury depends on duration of hypoxia and levels of inflammation persistence of neural insults may be short term, long term or permanent our treatment must be directed to, 1/1
1/2 1.drugs improving cerebral circulation(piracetam) 2.drugs improving nerve metabolism(citicoline, piracetam) 3.drugs restoring neurohormonal normalcy(mirtazapine) 4.drugs for neuronal hyperexcitability (divalprox) 4.drugs enhancing neuroplasticity(lithium, modafinil)
ANTI-COVID ANTIVIRALS, COMMONLY USED, EASILY AVAILABLE
HCQ IVM NITAZOX NICLOSAMIDE FEVIPIRAVIR MOLNUPIRAVIR(whenever available) ARTEMISIN+MEFLOQUINE FLUVOXAMIN+IVM PYRONARIDINE/PYRAMAX(if available)
https://twitter.com/drakchaurasia/status/1343867211933384705?s=19
ACUTE COVID FIRST LINE TREATMENT (fluvoxamine based)
FLUVOXAMINE-100mg twice daily + IVERMECTIN-12
AMBROXOL+NAC SPIRO+FRUSEMIDE BROMELIN ETORICOXIB/ETODOLAC RABEPRAZOLE
SIGMA AGONISTS FOR POTENTIAL USE IN SARS-COV2 commonly used and available compounds known to possess sigma agonist activity,
FLUVOXAMINE FLUOXETINE OPIPRAMOL BERBERINE
SEROTONIN EXESS
IN BRAIN CAUSES, SEROTONIN SYNDROME IN BLOOD CSUSES, ENDOTHELIAL DYSFUNCTION, THROMBOSIS AND MULTIPLE ORGAN FAILURE both are grossly different. one cause neurological dysfunction, other causes organ dysfunction.
after demonization of hcq and ivm, just shifting to,
NITAZOXANIDE FLUVOXAMINE NICLOSAMIDE MEFLOQUINE all are presumably available everywhere and a witty doc can use it to save his pts.
"SPIROLOLACTONE
spironolactone is big hope in treating post covid syndrome it has proved extremely effective in treating covid hypoxia(cutting down illness to about 2 weeks) *my last 2 months pt's feedbacks give me confidence of it's efficacy in post covid syndrome" 28 sept 20 https://t.co/rXiuYNczMV
PROPHYLAXIS PROTOCOL FOR COVID19
IVERMECTIN 12mg /weekly for 6-8 weeks
TAB HCQS-400 mg /weekly for 6-8 weeks (this is dose for prophylaxis)
the sample formulation for a post covid case (long houler), with POTS,
TAB CITICOLIN-500 1 tab once daily TAB CLONAZEPAM .25mg 1 tab once daily TAB MODAFINIL-100 1 tab daily(in morning) TAB CEREVATE 1 tab once daily