Appropriate thresholds for taxonomic annotation of viruses.

faylward / viralrecall

Detection of NCLDV signatures in 'omic data

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Appropriate thresholds for taxonomic annotation of viruses. #11

Closed MengzhiJ closed 2 years ago

MengzhiJ commented 2 years ago

Hi, I would like to know the appropriate threshold (min score and minvog) that I should set to mine the signal of giant viruses from many viral contigs. Thank you!

faylward commented 2 years ago

Sorry for my slow reply. I would recommend binning the contigs first and then running viralrecall on the bins. If you find a bin with mostly positive scores, and with NCLDV marker genes present, you can be confident that it is a draft NCLDV genome.