andrew-bortvin
commented
2 months ago | Exercise | Description | Completion |
|---|---|---|
| Q1.1 | Load DNM data | Y |
| Q1.2 | Tabulate paternally and maternally inherited DNMs per proband | Y |
| Q1.3 | Load age data into df | Y |
| Q1.4 | Combine age and DNM data | Y |
| Q2.1.1 | Plot maternal DNMs vs. maternal age | Y |
| Q2.1.2 | Plot paternal DNMs vs. paternal age | Y |
| Q2.2.0 | Fit linear regression model to data | Y |
| Q2.2.1 | Discuss "size" of relationship | Y |
| Q2.2.2 | Discuss significance of relationship | Y |
| Q2.3.0 | Fit linear regression model to data | Y |
| Q2.3.1 | Discuss "size" of relationship | Y |
| Q2.3.2 | Discuss significance of relationship | Y |
| Q2.4 | Predict # of paternal DNMs for proband with 50.5 yr old father at time of birth | Y |
| Q2.5.1 | Histogram of maternal DNMs per proband | Y |
| Q2.5.2 | Histogram of paternal DNMs per proband | Y |
| Q2.6.0 | Test significance between # of maternally vs. paternally inherited DNMs per proband | Y |
| Q2.6.1 | Justification for selection of statistical test | Y |
| Q2.6.2 | Interpretation of test results | Y |