search

ferrannadeu / IgCaller

Python program designed to reconstruct immunoglobulin gene rearrangements and oncogenic translocations from WGS, WES and capture NGS in lymphoid neoplasms.
Other
19 stars 8 forks source link

Modifying IgCaller for T-cell receptor (TCR) rearrangements #10

Open BramLimSJ opened 5 days ago

BramLimSJ commented 5 days ago

Hello,

I have some whole-genome sequencing BAM files of T-cell leukaemia. I was wondering how I can modify IgCaller to call T-cell receptor (TCR) rearrangements. Some guidance on how I can modify the code and what additional reference files I need will be very help.

Thank you very much!

ferrannadeu commented 4 days ago

Thank you for your message. We are indeed working on a new version of IgCaller that calls both IG and TCR rearrangements. I will write here again once the new version of the code is available on GitHub.

BramLimSJ commented 23 hours ago

This is amazing - thank you very much! I look forward it. Do you have an estimate of when this might be released?