review ContrastsMissing get_contrasts

fgcz / prolfqua

Differential Expression Analysis tool box R lang package for omics data

MIT License

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Open wolski opened 3 months ago

wolski commented 3 months ago

get_contrasts get_imputed_contrasts * missigness_impute_factors_interactions(pepIntensity, config, value = "long" ) *** .missigness_impute_interactions interaction_missing_stats get_contrast(ungroup(imp), config$table$hierarchy_keys(), Contr) aggregate_contrast(ungroup(imputed2), subject_Id = config$table$hierarchy_keys_depth()) ** summarize_stats

wolski commented 3 months ago

possible replace with -> get LOD -> impute -> build models with lm -> when computing contrasts update degrees of freedom etc.

wolski commented 3 months ago

update of statistics when computing interaction is still needed
- see vignette posthoc InteractionAnalysis in prolfquapp.
- https://github.com/prolfqua/prolfquapp/blob/master/vignettes/PostHocInteractionAnalysis.Rmd

wolski commented 3 months ago