search

fhormoz / caviar

52 stars 25 forks source link

Can I use case-control GWAS in eCAVIAR? #11

Closed Zepeng-Mu closed 3 years ago

Zepeng-Mu commented 5 years ago

Can I use OR from logistical regression as Z-score in eCAVIAR to do colocalization between two GWASs?

fhormoz commented 5 years ago

You need to convert the OR to z-score. You need to compute the log(OR) and divide it by the standard error of log (OR), so Z= log(OR)/se(log OR).