Day 4 Afternoon Exercise

[schidambaran]

Exercise	Description	Completion
Q1.1	Load DNM data	Yes
Q1.2	Tabulate paternally and maternally inherited DNMs per proband	Yes
Q1.3	Load age data into df	Yes
Q1.4	Combine age and DNM data	Yes
Q2.1.1	Plot maternal DNMs vs. maternal age	Yes
Q2.1.2	Plot paternal DNMs vs. paternal age	Yes
Q2.2.0	Fit linear regression model to data	Yes
Q2.2.1	Discuss "size" of relationship	Yes
Q2.2.2	Discuss significance of relationship	Yes
Q2.3.0	Fit linear regression model to data	Yes
Q2.3.1	Discuss "size" of relationship	Yes
Q2.3.2	Discuss significance of relationship	Yes
Q2.4	Predict # of paternal DNMs for proband with 50.5 yr old father at time of birth	Yes
Q2.5.1	Histogram of maternal DNMs per proband	Yes
Q2.5.2	Histogram of paternal DNMs per proband	Yes
Q2.6.0	Test significance between # of maternally vs. paternally inherited DNMs per proband	Yes
Q2.6.1	Justification for selection of statistical test	Yes
Q2.6.2	Interpretation of test results	Yes

Excellent work!

Comments: - Please make sure you comment on the "size" of the relationships for Q2.2.1 and Q2.3.1 (look at the value of the slope for each model) - Please complete Q2.6

[schidambaran]

Updated rubric based on assignment resubmission.