Open firasm opened 9 years ago
firasm
commented
9 years ago From: Morrison, C., Stanisz, G., & Henkelman, R. M. (1995). Modeling magnetization transfer for biological-like systems using a semi-solid pool with a super-Lorentzian lineshape and dipolar reservoir. Journal of Magnetic Resonance. Series B, 108(2), 103–113.
found another version of a super lorentzian...which happens to be the same as the one used above
ayandeb
commented
6 years ago Here the lineshape has unit of seconds if T2 is in second. We cannot fit g(2pidelta) to Z-spectra since g has unit of second and Z-spectra is unitless. We can only club g with Morrison equation only. I want to fit Super-Lorentzian lineshape (unitless) with MT portion of Z-spectra (unitless). Could you please tell me how we can write Super-Lorentzian lineshape without any unit. Please mail me or contact me at ayan.newton@gmail.com. It's very urgent to solve my problem. Kindly help me as soon as possible.
In the literature, most people fit CEST spectra to a Super Lorentzian, rather than a lorentzian.
This paper (Xavier Golay is in the list of authors) describes some reasons why the Super Lorentzian is preferred and is a better model for the line shape.
where θ is the dipole orientation angle with respect to the external magnetic field
This is something for us to consider before we get too invested in the Lorentzian line shape when fitting a model to the data.
Sinclair, C. D. J., Samson, R. S., Thomas, D. L., Weiskopf, N., Lutti, A., Thornton, J. S., & Golay, X. (2010). Quantitative magnetization transfer in in vivo healthy human skeletal muscle at 3 T. Magnetic Resonance in Medicine, 64(6), 1739–1748. doi:10.1002/mrm.22562.