What is the difference between CMO's and hash antibodies.

florekem / singleCell_LAB

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What is the difference between CMO's and hash antibodies. #8

Open florekem opened 1 week ago

florekem commented 1 week ago

3` chemistry uses CMO's for multiplexing. 5` chemistry uses hash antibodies. What is the difference? May it be the reason HTODEmux() is not working properly?

florekem commented 1 week ago

Cell Multiplexing Oligos (CMOs) or Cholesterol Modified Oligos (CMOs) https://pmc.ncbi.nlm.nih.gov/articles/PMC8851857/#Sec9 ?