search

francescojm / CRISPRcleanR

Unsupervised correction of gene independent cell responses to CRISPR-cas9
Other
48 stars 13 forks source link

Gene symbols #5

Open eudaldt opened 3 years ago

eudaldt commented 3 years ago

I am writing to you because I am collaborating in a CRISPR/Cas9 knockout screening analysis. We are using the GeCKO v2 gRNA library and we found that a huge number of gene symbols are outdated. I found your R program CRISPRcleanR and, according to the steps described in https://rdrr.io/github/francescojm/CRISPRcleanR/man/GeCKO_Library_v2.html, you updated the gene symbols but I downloaded your Rdatafile and I observed that there are many gene symbols still deprecated. Did you only update some of them?

francescojm commented 2 years ago

Hi eudaldt, we are currently updating all the built in library annotation data objects to replace deprecated gene symbols with their most recent version from HGNC