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fritzsedlazeck / Sniffles

Structural variation caller using third generation sequencing
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variant allele frequency adjustment #493

Closed abosco4406 closed 1 month ago

abosco4406 commented 4 months ago

Hello, I am looking to see if there's a way to adjust the variant allele frequencies (VAF) in mosaic mode to detect below 5%?

hermannromanek commented 4 months ago

Hi @abosco4406

The parameter --mosaic-af-min can be used for this to set a minimum threshold.

HTH, Hermann