search

fritzsedlazeck / Sniffles

Structural variation caller using third generation sequencing
Other
561 stars 95 forks source link

Breakpoints of SVs #532

Open reshu23 opened 9 hours ago

reshu23 commented 9 hours ago

Dear Team, I have question related to reported break points of SVs by Sniffles. Are breakpoints detected at single nucleotide resolution(exact breakpoints)? Thank you.

tuannguyen8390 commented 9 hours ago

Yes, you can look at the flag STDEV_POS

FILTER=

Variant with STDEV_POS=0 variant would have "perfect" breakpoint. But some variability perhaps might be expected depending on sequencing technology.

reshu23 commented 9 hours ago

Thank you. I will check it.