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fteufel / alphafold-peptide-receptors

Identifying peptide-receptor interactions using AlphaFold-Multimer
https://pubs.acs.org/doi/10.1021/acs.jcim.3c00378
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receptor library size #1

Open ryupath opened 7 months ago

ryupath commented 7 months ago

I tried to get receptor library from uniprot, according to your paper’s instructions, then I found 4222 proteins without amino acid length filter. Even with amino acid length filter of <800 AAs, there are still 3371 proteins remain. How can I reproduce your results?

fteufel commented 7 months ago

Hi, Uniprot is always changing, and in addition to the length criterion we excluded single-tm proteins. For full reproduction, I would recommend using the file provided in the repo https://github.com/fteufel/alphafold-peptide-receptors/blob/main/data/human_receptors.csv