Modeling 'Therapeutic Intervention' (as a Domain Entity)

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We need to model an object for type/class-level representations of Therapeutic Interventions (as opposed to specific instances that occur on specific occasions toward particular patients). The driving use case for this is the descriptor/object in Therapeutic Response Annotations, as described in #31. A few initial thoughts are below:

• A therapeutic intervention is a process in which some form of treatment is administered to a patient - be it chemical (e.g. a drug), physical (e.g. acupuncture, radiation), behavioral, etc.
• The model will have to support simple interventions comprised of a single type of drug exposure, and combination treatments that include multiple exposures/interventions as part (e.g. multiple drugs).
• It may also need to support modeling of temporal aspects of interventions - including things like sequence in which interventions are applied, intervals between interventions, dosage or duration of treatments, etc.
• It may have to include representations of specific drugs (e.g. erlotinib) as well as drug categories (e.g. EGFR inhibitors)

Once we have clearly defined requirements and a straw man proposal, we should reach out to other GA4GH groups that may have need for a similar object (e.g. ClinPheno), and also consider if/how we might leverage SchemaBlocks here.

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For now (for v0) we have defined the very simple and naive model here, which will support initial testing, but ultimately be replaced by a richer model developed in collaboration with other groups.