search

ga4gh / vrs-python

GA4GH Variation Representation Python Implementation
https://github.com/ga4gh/vrs
Apache License 2.0
51 stars 27 forks source link

Add support for protein variation in translate_to() #133

Open jarbesfeld opened 1 year ago

jarbesfeld commented 1 year ago

translate_to() currently supports translation to HGVS strings for nucleic acid variation but not protein variation

korikuzma commented 1 year ago

For now, we won't worry about trying to normalize protein variants since biocommons.hgvs does not support protein normalization yet. Will make an issue soon to address.

korikuzma commented 1 year ago

This issue will also be helpful for our VarCat project. Given gnomad vcf representation, we use the VICC Variation Normalizer to translate to the VRS Object on the protein sequence. We need to be able to get the protein hgvs expression from this.

github-actions[bot] commented 1 year ago

This issue was marked stale due to inactivity.