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geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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Matrix: mitotic chromosome segregation /cytoplasmic translation #2466

Closed ValWood closed 5 years ago

ValWood commented 5 years ago

eIF4E1 | eukaryotic translation initiation factor 4E1 | Drosophila melanogaster |   | protein | FB | 0260/090587/11

This is a . screen and it identifies quite a few upstream things (others will probably pop out in other intersections).

They don't study these any further and they say:

A simple explanation for the high representation of these factors is that the observed mitotic defects are indirectly caused by a lack of transcription, splicing, or translation of mitotic regulators. However, it is also possible that at least some of these genes might directly regulate mitosis in a manner independent of their functions in transcription, mRNA splicing, or translation.

Since most are likely indirect effects I wouldn't make these annotations from this screen.

hattrill commented 5 years ago

Removed: phenotype

ValWood commented 5 years ago

Ah this is the same gene /paper. I thouhg it would pop up again!

hattrill commented 5 years ago

There were two papers - equally nuked!