Remove GO:0008375 from Glycosyl transferase, family 14 (IPR003406)

[sjm41]

Glycosyl transferase, family 14 (IPR003406) corresponds to CAZT GT14 family, which includes several different functional activities, not all of which are acetylglucosaminyltransferases: http://www.cazy.org/GT14.html

E.g. some GT14 members are xylosyltransferases, as noted in the 'family relationships' section of the InterPro report.

It's therefore incorrect to associate "acetylglucosaminyltransferase activity (GO:0008375)" with IPR003406 - please remove.

Thanks. @hattrill @happy-lorna

[typhainepl]

Thanks for highlighting this. I have removed the GO term from the InterPro entry. The changes will be visible in the next InterPro release (78.0).

[sjm41]

Thanks!

[cmungall]

I'm curious why the decision was made to remove this altogether than to go up a level to

id: GO:0016757
name: transferase activity, transferring glycosyl groups
namespace: molecular_function
alt_id: GO:0016932
def: "Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_yeast
synonym: "glycosyltransferase activity" EXACT []
synonym: "transferase activity, transferring other glycosyl groups" NARROW []
synonym: "transglycosidase activity" EXACT []
synonym: "transglycosylase activity" EXACT []
xref: EC:2.4
is_a: GO:0016740 ! transferase activity

this seems consistent with http://www.cazy.org/GT14.html

[pgaudet]

@typhainepl

[sjm41]

I agree with @cmungall - sorry, I should have suggested this at the time. Please add GO:0016757 to IPR003406.

[typhainepl]

I have updated the InterPro entry. The changes will be visible in InterPro 83.0.

[sjm41]

Thanks.