geneontology / go-annotation

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IPR009580 Phospho-ethanolamine N-methyltransferase #302

Closed gocentral closed 8 years ago

gocentral commented 17 years ago

Hi,

I'm not sure PIG-F is actually a methyltransferase. It seems to be some sort of regulatory subunit for PIG-O and possibly PIG-G/GPI7, which are phosphoethanolamine methyltransferases.

See PMID: 12655644 and PMID: 15632136

It seems that this methyltransferase name comes from Pfam and/or Panther. I can submit requests to those databases as well if necessary.

Thanks,

Karen

Reported by: kpilcher

Original Ticket: "geneontology/annotation-issues/302":https://sourceforge.net/p/geneontology/annotation-issues/302

gocentral commented 17 years ago

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Hi Karen,

I submitted this family to Pfam and it is described as

phospho-ethanolamine N-methyltransferase, the description was derived from the SGD annotation for "GPI phosphoethanolamine N-methyltransferase activity"

which does look incorrect, so I will query this with them, and get teh naem of the Pfam family changes if this is misleading...you are right it doesn't fall into the methytransferase superfamily so this activity is unlikely.

Val

Original comment by: ValWood

gocentral commented 17 years ago

Original comment by: mah11

gocentral commented 17 years ago

Logged In: YES user_id=545117

Name, short name and text updated. Sandra

Original comment by: orchard

gocentral commented 17 years ago

Original comment by: orchard