PTHR13831 - PTN000352669

[ValWood]

I don't think

slm9 |   | IBA with PTN000352669 , S000005564 , S000000104

is a

GO:0003714 | transcription corepressor activity

(is a histone chaperone)

[ValWood]

GO:0003714 transcription corepressor activity A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes

this does not seem to fit histone chaperones (although I would agree that we don't have a very good way of describing the molecular function of these at present...

[pgaudet]

to see with @colinlog I think it's OK to say that histone chaperones and modifiers are co-regulators.

Right not that IBA is gone.

[ValWood]

I'd like to discuss histone chaperones for a few minutes if possible (an if they are coregulators, but also a couple of other questions)

[colinlog]

Hi Val, As usual the answer to your question is going to be a little ambiguous I am afraid. Will we discuss this at 13h30 (12h30 in UK) during the transcription call today? Cheers, Colin

On Fri, Nov 25, 2022 at 12:12 PM Val Wood @.***> wrote:

I'd like to discuss histone chaperones for a few minutes if possible (an if they are coregulators, but also a couple of other questions)

— Reply to this email directly, view it on GitHub https://github.com/geneontology/go-annotation/issues/3414#issuecomment-1327343537, or unsubscribe https://github.com/notifications/unsubscribe-auth/ALZVLKHQBB3IAUXAZICYBN3WKCNJTANCNFSM4TAWDF5Q . You are receiving this because you were mentioned.Message ID: @.***>

[pgaudet]

@srengel @marekskrzypek

Annotations to S000005564 and CAL0000181007 GO:0006368 transcription elongation by RNA polymerase II promoter should be replaced by the newer term GO:0140673 transcriptional elongation-coupled chromatin remodeling

Thanks, Pascale

[srengel]

SGD done.

[marekskrzypek]

CGD done

[pgaudet]

Both PAINT and primary annotations have been fixed, closing.