geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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PANTHER:PTN000306261 #4777

Closed ValWood closed 1 year ago

ValWood commented 1 year ago

spt4 | DSIF transcription elongation factor complex subunit Spt4 |   | regulation of transcription elongation by RNA polymerase II |   | GO_Central | Schizosaccharomyces pombe | IBA | PANTHER:PTN000306261SGD:S000003295 more... | suppressor of ty 4 pthr12882 | protein |   | PMID:21873635 | 20230110

Annotation, I think. This is directly involved in elongation -dependent remodelling. If mutated you get serious initiation, but this isn't "regulation" in the GO sense (as in "control")

see https://github.com/geneontology/go-annotation/issues/4191 for background

marcfeuermann commented 1 year ago

There are no less than 12 distinct transcription regulation terms annotated for this family and a single direct term. I've made the change.

ValWood commented 1 year ago

Yep, all of the early papers call it "regulation" so I guess this is one we will be addressing for years...