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geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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TreeGrafter issue PANTHER:PTHR22812:SF112 284812 and PAINT PANTHER:PTN000517042 #5003

Open ValWood opened 7 months ago

ValWood commented 7 months ago

PANTHER:PTN000517042 UniProtKB:P40381 | swi6 | involved_in | GO:0000122    negative regulation of transcription by RNA polymerase II | ECO:0000318   IBA | GO_REF:0000033 | FB:FBgn0030082 more... | 284812 Schizosaccharomyces pombe (strain 972 / ATCC 24843) | GO_Central |  

UniProtKB:P40381 swi6 involved_in GO:0000122 negative regulation of transcription by RNA polymerase II ECO:0007826 IEA GO_REF:0000118
PANTHER:PTHR22812:SF112 284812 Schizosaccharomyces pombe (strain 972 / ATCC 24843) TreeGrafter

Swi6 isn't negative regulation of transcription as it doesn' act on the transcription machinery to affect gene expression it does do gene silencing via maintaining heterochromatin (via multiple pathways)

will query the FB annotation

ValWood commented 7 months ago

note to self, also UniProtKB:P40381 | swi6 | involved_in | GO:0090053    positive regulation of pericentric heterochromatin formation | ECO:0000315   IMP | PMID:19136623 |   | 284812 Schizosaccharomyces pombe (strain 972 / ATCC 24843) | CACAO

(direct, not regulation of)

UniProtKB:P40381 swi6 involved_in GO:0090053 positive regulation of pericentric heterochromatin formation ECO:0000315 IMP PMID:19136623
284812 Schizosaccharomyces pombe (strain 972 / ATCC 24843) CACAO