geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
BSD 3-Clause "New" or "Revised" License
34 stars 10 forks source link

PTN000229249 (GUANYLYL CYCLASE (PTHR11920)) #5108

Closed sjm41 closed 7 months ago

sjm41 commented 7 months ago

This node is annotated with both adenylate cyclase activity and guanylate cyclase activity.

I think it should just have guanylate cyclase activity - that would fit the fly proteins at least, and there's a more source annotations for that activity compared to the adenylate cyclase activity. But it might not be as simple as that....

marcfeuermann commented 7 months ago

Indeed, adenylate cyclase acrtvity has been removed. Annotation comes from a possible horizontal gene transfer by MYCTU and an ancestral duplication in DICDI/DICPU.

sjm41 commented 7 months ago

Thanks Marc!