geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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TreeGrafter problems, Google sheet #5129

Open ValWood opened 3 months ago

ValWood commented 3 months ago

Going forward, I will add problems to this Googlesheet:

https://docs.google.com/spreadsheets/d/1AME11i0L9TtGqMINUECFKgchKfZWNdk7RvaGM6VyeBY/edit#gid=0

ValWood commented 2 months ago

Some more annotations. These I double checked all , they are not PAINTED (I removed the legacy filters, but most TreeGrafter are still present)

PTHR11079:SF149 https://www.pombase.org/gene/SPCC965.14c is cytosine deaminase NOT GO:0052717 tRNA-specific adenosine-34 deaminase activity GO:0002100 tRNA wobble adenosine to inosine editing IEA with PTHR11079:SF149

bir1 https://www.pombase.org/gene/SPCC962.02c GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA with PTHR10044:SF139 GO_REF:0000118
GO:0061630 ubiquitin protein ligase activity IEA with PTHR10044:SF139 GO_REF:0000118

rnc1 https://www.pombase.org/gene/SPCC757.09c GO:0045292 mRNA cis splicing, via spliceosome IEA with PTHR10288:SF142 GO:0000381 regulation of alternative mRNA splicing, via spliceosome IEA with PTHR10288:SF142 Applies to all species

jmj4 https://www.pombase.org/gene/SPCC622.19 GO:0031591 wybutosine biosynthetic process IEA with PTHR12461:SF97

ria1 https://www.pombase.org/gene/SPCC553.08c GO:0003746
translation elongation factor activity IEA with PTHR42908:SF3 GO_REF:0000118 Applies to all species?

sgo2 https://www.pombase.org/gene/SPAC15A10.15 GO:0051177 meiotic sister chromatid cohesion IEA with PTHR21577:SF3 (sgo2 is mitotic)

met26
homocysteine methyltransferase Met26 GO:0008705 methionine synthase activity GO:0008705 methionine synthase activity IEA with PTHR30519:SF0 GO:0005576 extracellular region IEA with PTHR30519:SF0 Is not methionine synthase activity

fzr2 meiotic fizzy-related APC coactivator Fzr2 GO:0005680 anaphase-promoting complex GO:0005680 anaphase-promoting complex IEA with PTHR19918:SF66 anaphase-promoting complex, is an activator, applies to all species

srw1 substrate-specific mitotic G1 APC coactivator Srw1/Ste9 GO:0005680 anaphase-promoting complex, is an activator, applies to all species GO:0005680 anaphase-promoting complex IEA with PTHR19918:SF1 anaphase-promoting complex, is an activator, applies to all species

taf13 transcription factor TFIID complex subunit Taf13 GO:0003713 transcription coactivator activity GO:0003713 transcription coactivator activity IEA with PTHR11380:SF5 (Applies to all sources, is GTF)

csn4 COP9/signalosome complex subunit Csn4 GO:0008541 proteasome regulatory particle, lid subcomplex GO:0008541 proteasome regulatory particle, lid subcomplex IEA with PTHR10855:SF11 (related to proteasome)

gem1 ERMES complex GTPase subunit Gem1 GO:0047497 mitochondrion transport along microtubule GO:0047497 mitochondrion transport along microtubule IEA with PTHR24072:SF73 (Indirect)

vhc1 vacuolar membrane cation-chloride cotransporter Vhc1 GO:1990573 potassium ion import across plasma membrane GO:1990573 potassium ion import across plasma membrane IEA with PTHR11827:SF72

pxl1 paxillin-like protein Pxl1 GO:0003712 transcription coregulator activity GO:0003712 transcription coregulator activity IEA with PTHR24205:SF4 (not a txn coregulator, any species)

dre4 splicing associated factor Dre4 GO:0003712 transcription coregulator activity GO:0003712 transcription coregulator activity IEA with PTHR15377:SF3 GO_REF:0000118

gnd1 https://www.pombase.org/gene/SPBC660.16 GO:0008114 phosphogluconate 2-dehydrogenase activity IEA with PTHR11811:SF25 is GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity

https://www.pombase.org/gene/SPCC126.13c sap18 exon junction complex associated protein Sap18 GO:0003714 transcription corepressor activity GO:0003714 transcription corepressor activity IEA with PTHR13082:SF0

dcp2 https://www.pombase.org/gene/SPAC19A8.12 dcp2 mRNA decapping complex catalytic subunit Dcp2
NOT GO:0034353 mRNA 5'-diphosphatase activity IEA with PTHR23114:SF17

ValWood commented 2 months ago

@pgaudet I thought this migth be useful

I remembered an issue about these

SPAC11E3.12 mitochondrial thioredoxin family protein, implicated in sulfur cluster assembly GO:0006120 mitochondrial electron transport, NADH to ubiquinone SPAC11E3.12 mitochondrial thioredoxin family protein, implicated in sulfur cluster assembly GO:0003954 NADH dehydrogenase activity GO:0006120 mitochondrial electron transport, NADH to ubiquinone IEA with PTHR10371:SF3 GO:0003954 NADH dehydrogenase activity IEA with PTHR10371:SF3 GO_REF:0000118 These refer to

See this older ticket: https://github.com/geneontology/go-annotation/issues/2104 I wonder if the bug mentioned here is not fixed for TreeGrafter?