PTN000806614 (PTHR10155) - Githubissues

geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.

BSD 3-Clause "New" or "Revised" License

34 stars 10 forks source link

PTN000806614 (PTHR10155) #5191

Closed sjm41 closed 4 months ago

sjm41 commented 5 months ago

PTHR ID & PTN node: PTN000806614 (PTHR10155)
Sequences with problematic annotation (ID + gene/protein name): fly Socs44A, Socs16D, Socs36E
Type of Issue: Erroneous source or erroneous propagation, or other issue erroneous propagation

This node is labelled 'PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (PTHR10155)' and has annotations consistent with that label.

But PTHR10155 also contains 'SOCS' proteins, involved in cytokine signalling (and not PI3K singling AFAIK). E.g. https://www.pantherdb.org/genes/geneList.do?searchType=basic&loggedPrivilege=false&fieldName=all&fieldValue=PTHR10155*&listType=1&organism=Homo%20sapiens

I think this needs splitting?

marcfeuermann commented 4 months ago

I've completely re-annotated the family. SOCS proteins have now there specific annotations.