IPR036549 "Cytochrome c oxidase, subunit VIb also matches coa6 assembly factor

geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.

BSD 3-Clause "New" or "Revised" License

31 stars 10 forks source link

IPR036549 "Cytochrome c oxidase, subunit VIb also matches coa6 assembly factor #5206

Closed ValWood closed 4 weeks ago

ValWood commented 1 month ago

InterPro ID / label

IPR036549 https://www.pombase.org/gene_subset/interpro:IPR036549

Example sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPBC24C6.13

Description of issue

Unfortunate!

The panther family seems to split, so maybe InterPor could use Panther here? PTHR47677 PANTHER CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 PTHR46281 PANTHER CYTOCHROME C OXIDASE SUBUNIT 6B IPR003213 Cytochrome c oxidase, subunit

sarach06 commented 1 month ago

Hi Val, Thank you for highlighting this. IPR036549 is an Homologous superfamily entry which includes G3D and Superfamily signatures, so we can't do much other than updating the description, which I did. The PANTHER signatures are integrated in these InterPro entries: [https://www.ebi.ac.uk/interpro/entry/InterPro/IPR003213/] for PTHR46281 and [https://www.ebi.ac.uk/interpro/entry/InterPro/IPR048281/] for PTHR47677. Hope this helps. Best wishes, Sara

ValWood commented 1 month ago

Could you remove respiratory chain complex IV (GO:0045277) because this is incorrect for Coa6

but you could add it instead to https://www.ebi.ac.uk/interpro/entry/InterPro/IPR003213/ which covers only the cytochrome oxidase subunit so the mapping isn't lost.

sarach06 commented 1 month ago

Hi Val, Yes, forgot to say that the term was removed from that entry. I added it to IPR003213. Thanks for pointing this! Best wishes Sara