geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport | IBA with S000001869 , PTN000398233 #5296

Closed ValWood closed 2 months ago

ValWood commented 3 months ago

GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport | IBA with S000001869 , PTN000398233

This is a phenotype from an early paper 1996 before the role in GPI biosynthesis was unravelled It seems to be because this step required for their efficient incorporation into COPII transport vesicles through association with cargo receptors but transport seems to be indirect. There is only a problem in the mutant because its required upstream

The later 2004 paper showing the role in GPI metabolism says The mutant cells showed a clear delay in the maturation of GPI-APs in the Golgi and accumulation of GPI-APs in the ER. Thus, the GPI inositol deacylation is important for efficient transport of GPI-APs from the ER to the Golgi.

https://www.pombase.org/gene/SPAC824.02 bst1

Annotation

marcfeuermann commented 2 months ago

This is again a duplicated ticket that has been recently addressed. https://github.com/geneontology/go-annotation/issues/5255 Please check before submitting new issues. Thanks, Marc.

ValWood commented 2 months ago

Sorry, I usually search, I must have done something wrong here. v