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geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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Review annotations to GO:0030685 nucleolar preribosome #5319

Closed ValWood closed 3 months ago

ValWood commented 4 months ago

Dear all,

The proposal has been made to obsolete GO:0030685 nucleolar preribosome see https://github.com/geneontology/go-ontology/issues/24626

Experimental annotations that need to be reviewed are here: https://docs.google.com/spreadsheets/d/1LmooGZhDxI8KlbzH3ukfE72f5L-SmzKvOLunFc0R_uE/edit?gid=0#gid=0

Impacted groups: PomBase 71 SGD 2

Thanks.

ValWood commented 4 months ago

90S preribosome is a better replacement:

The 90S preribosome is an early pre-ribosomal complex involved in the biogenesis of the small ribosomal subunit (40S) in eukaryotic cells. This complex assembles in the nucleolus, a subnuclear structure where ribosome biogenesis occurs. The 90S preribosome undergoes a series of maturation steps within the nucleolus before giving rise to the pre-40S and pre-60S subunits, which are then transported to the cytoplasm for final maturation and assembly into functional ribosomes.

ValWood commented 4 months ago

It should be replaced by "preribosome" because

GO:0030686    90S preribosome | is_a GO:0030687    preribosome, large subunit precursor | is_a GO:0030688    preribosome, small subunit precursor | is_a GO:0032040    small-subunit processome can all be nucleolar