ValWood
commented
2 months ago There also seems to be overannotation of processes too here:
https://www.pombase.org/gene/SPAC11D3.08c
It seems unlikely that SPAC11D3.08c transports ALL
| GO:0003333 | amino acid transmembrane transport | IBA with PTN000209009 , locus:2038811 , CAL0000188952 , S000002369 | GO_REF:0000033 | 48 | |
|---|---|---|---|---|---|
| - | GO:1905039 | carboxylic acid transmembrane transport | IBA with PTN000209009 , S000002369 , locus:2038811 , CAL0000188952 | GO_REF:0000033 | 45 |
| - | GO:0015812 | gamma-aminobutyric acid transport | IBA with locus:2038811 , S000002369 , PTN000209009 , CAL0000188952 , Q5B918 | GO_REF:0000033 | 8 |
| - | GO:0015718 | monocarboxylic acid transport | IBA with PTN000209009 , S000002369 , locus:2038811 , CAL0000188952 |
and S000002369 does not seem to be annotated to all of them. These are not going to be fun!
S. pombe has 8 amino acid transporter family members annotated to gamma-aminobutyric acid transmembrane transporter which seems unlikely. (especially since by most methods TPO5 and HNM1 are as closely related)
Sequences with problematic annotation (ID + gene/protein name):
Type of Issue: Erroneous source or erroneous propagation, or other issue
Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).