geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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vacuolar protein processing PTN001121786/PTN000337666 #5474

Open ValWood opened 1 month ago

ValWood commented 1 month ago

Both are readouts, have been removed from SGD

GO:0006624 | vacuolar protein processing | IBA with S000006157 , PTN001121786

GO:0006624 | vacuolar protein processing | IBA with S000004055 , PTN000337666

pgaudet commented 1 month ago

If all annotations are readouts, should term be obsoleted?

ValWood commented 1 month ago

I did wonder about that, but I don't think so. All annotations for this paper were readouts (because the assay can identify anything from the proteins required for the processing events entering the secretory pathway onwards, but there are genes that are involved more directly in "vacuolar protein processing". Most of the remaining annotations are to the protease, but there will be other GPs which affect this process more directly by activating the protease etc.