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Review annotations: sequestering process terms and regulation of sequestering process #5497

Open edwong57 opened 3 weeks ago

edwong57 commented 3 weeks ago

Dear all,

The proposal has been made to obsolete the following terms:

GO:0006880 | intracellular sequestering of iron ion | 39 GO:0006881 | extracellular sequestering of iron ion | 15 GO:0007253 | cytoplasmic sequestering of NF-kappaB | 36 GO:0010891 | negative regulation of sequestering of triglyceride | 11 GO:0010890 | positive regulation of sequestering of triglyceride | 10 GO:0030730 | sequestering of triglyceride | 11 GO:0010889 | regulation of sequestering of triglyceride | 1 GO:0042137 | sequestering of neurotransmitter | 2 GO:0042989 | sequestering of actin monomers | 24 GO:0042994 | cytoplasmic sequestering of transcription factor | 18 GO:0051220 | cytoplasmic sequestering of protein | 23 GO:0032119 | sequestering of zinc ion | 5 GO:0051238 | sequestering of metal ion | 6 GO:0097578 | sequestering of copper ion | 2 GO:0097577 | sequestering of iron ion | 4 GO:1990659 sequestering of manganese ion|0

see https://github.com/geneontology/go-ontology/issues/17075

Experimental annotations that need to be reviewed are here: https://docs.google.com/spreadsheets/d/1WM-8BXKb1WMamR5ONCw3hxtppqQ3CR1ZVAxBalgjpGE/edit?usp=sharing

Impacted groups: AgBase 12 ARUK-UCL 1 BHF-UCL 24 CAFA 3 dictyBase 2 DisProt 5 FlyBase 19 GeneDB 1 GO_Central 3 MGI 18 ParkinsonsUK-UCL 2 PINC 7 PseudoCAP 6 RGD 26 SGD 4 UniProt 74 WB 4

Mappings that need to be reviewed: (InterPro2GO, UniProt-Keywords, UniRule)

GO:0006880 interpro2go InterPro:IPR030909 IMEF encapsulin system ferritin-like cargo > GO:intracellular sequestering of iron ion ; GO:0006880 GO:0006880 unirule2go UniRule:UR001903787 > GO:intracellular sequestering of iron ion ; GO:0006880

Thanks.

edwong57 commented 3 weeks ago

SGD done

pgaudet commented 3 weeks ago

@Antonialock From this sentence in PMID:8797820

Thus, the rescue of nuclear localization of Myf5 by the SV40 NLS suggests that I-mfa sequesters myogenic regulatory factors in the cytoplasm through direct protein interaction which masks the NLS of these factors.

I would say this is negative regulation of some signaling pathway?

slaulederkind commented 3 weeks ago

RGD finished.

RLovering commented 2 weeks ago

UCL done

sarach06 commented 1 week ago

Hi, Thank you very much. I have removed GO:0006880 from the InterPro entry you mentioned. This will be visible in InterPro release 103.0. Best, Sara