Closed gocentral closed 9 years ago
Original comment by: mah11
Original comment by: mah11
"DNA damage response" comment addressed in ticket # 3073343.
Original comment by: livstone
Restricted the 2 "response to" terms (UV-B and X-ray) to metazoa.
Original comment by: livstone
Restricting "intra-S DNA damage checkpoint" to metazoa. This should cover the parent term "cell cycle arrest," too
Original comment by: livstone
Restricted double-strand break repair to metazoa. At this point, all of these comments have been addressed by restricting the annotations in question to metazoa.
Original comment by: livstone
Original comment by: livstone
fission yeast msh2 is fairly well characterised and is involve din a mismatch repair pathway.
Inappropriate annotation transfer includes cell cycle arrest PANTHER:PTHR11361_AN159 double-strand break repair PANTHER:PTHR11361_AN159 intra-S DNA damage checkpoint PANTHER:PTHR11361_AN159 (these should be ermoved as checkppint signalling activation and responses are not fully conserved and these ar not implicated in checkpoint responses in this organism)
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis ISS (PAINT_REF:0011361) with PANTHER:PTHR11361_AN159 fission yeast has no p53 pathway (not this need a taxon lag0
response to UV-B PANTHER:PTHR11361_AN159 response to X-ray PANTHER:PTHR11361_AN159 ...indirect, uninformatice, see response to discussions
Reported by: ValWood
Original Ticket: geneontology/annotation-issues/819