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geneontology / go-annotation

This repository hosts the tracker for issues pertaining to GO annotations.
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SP_KW:KW-0805 KW mapping #956

Closed gocentral closed 1 year ago

gocentral commented 12 years ago

RNA polymerase I upstream activation factor complex subunit Rrn10 is mapping to regulation of transcription, DNA-dependent
but this is directly involved in transcription from RNA polymerase I promoter so this would be a more appropriate mapping

Reported by: ValWood

Original Ticket: geneontology/annotation-issues/957

gocentral commented 12 years ago

I am not sure about this one. i need to check with Karen.

Original comment by: ValWood

gocentral commented 12 years ago

Hi Val,

Karen passed this one along to me.

I agree that Rrn10 mapping directly to transcription from RNA pol I promoter instead of the regulation term is more appropriate.

Based on cerevisiae literature, the Pol I UAF complex is part of the pol I preinitiation complex. It's the first member to bind to DNA and recruits other members of the PIC to the promoter.

-Julie

Original comment by: juliep

gocentral commented 9 years ago

Sent to UniProt.

Original comment by: rachhuntley

ValWood commented 8 years ago

nope still present:

http://www.ebi.ac.uk/QuickGO/GProtein?ac=Q10360 Q10360 rrn10 GO:0006355 regulation of transcription, DNA-templated P IEA UniProt Keywords2GO (UniProtKB/Swiss-Prot entries) UniProtKB-KW:KW-0805

ValWood commented 8 years ago

This one is hardly surprising as we had an experiemental annotation to a regulation term, now fixed

mcourtot commented 8 years ago

Thanks - assigning myself and tagging for bulk submit to UniProt curators later.

sylvainpoux commented 6 years ago

Hi, I see more a problem of ontology here: the KW maps to regulation of GO:0006355; regulation of transcription, DNA-templated, which is imprecise, but not incorrect.

GO:0006361 transcription initiation from RNA polymerase I promoter would be of course better and ideally GO:0006361 and GO:0006355 should be directly linked.

Unfortunately, GO:0006361 and GO:0006355 are related by the parent 'GO:0006351 transcription, DNA-templated'

I don't think we can do something for this

Sylvain

ValWood commented 6 years ago

Hi Sylvain,

I'm confused why not map to GO:0006361 transcription initiation from RNA polymerase I promoter instead? since it is directly involved, not regulating?

val

ValWood commented 1 year ago

The #Transcription regulation is still there (in addition to transcription)., and should probably be removed.

However it seems that GO annotations are no longer generated from this mapping, so this issue can close.