geneontology / go-announcements

Announcements related to ontology changes that may impact groups using GO, such as obsoletions, merges, etc.
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Obsoletion notice: GO:0044736 acid-sensing ion channel activity & regulation children #626

Closed pgaudet closed 9 months ago

pgaudet commented 9 months ago

Dear all,

The proposal has been made to obsolete GO:0044736 acid-sensing ion channel activity & its regulation children. The reason for obsoletion is that this activity represents a gene family with GO:0160128 pH-gated channel activity.

Replacements: GO:0044736 acid-sensing ion channel activity >> GO:0160128 pH-gated channel activity

Consider: GO:1901585 regulation of acid-sensing ion channel activity >> GO:0099106 ion channel regulator activity GO:1901586 negative regulation of acid-sensing ion channel activity >> GO:0008200 ion channel inhibitor activity GO:1901587 positive regulation of acid-sensing ion channel activity >> GO:0099103 channel activator activity (0 annotations).

There are 9 annotations to these terms, see https://github.com/geneontology/go-annotation/issues/4849 by UniProt, MGI and FlyBase. There is one Reactome mapping. These terms are not present in any subsets.

You can comment on the ticket: https://github.com/geneontology/go-ontology/issues/26520

Thanks