geneontology / go-announcements

Announcements related to ontology changes that may impact groups using GO, such as obsoletions, merges, etc.
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Obsoletion notice: GO:0030580 quinone cofactor methyltransferase activity & substrate-specific children #639

Closed pgaudet closed 9 months ago

pgaudet commented 9 months ago

Dear all,

The proposal has been made to obsolete

GO:0043429 2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity GO:0043428 2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity GO:0043430 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity GO:0043334 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity GO:0043333 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity

since these represent species-specific substrates, as stated in the EC comment: "Ubiquinones from different organisms have a different number of prenyl units" and "However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units.". These will be replaced by the parent term " GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"

The parent of GO:0008425, 'GO:0030580 quinone cofactor methyltransferase activity' will also be obsoleted and replaced by GO:0008425, since these describe the same reaction.

Annotations are here: https://github.com/geneontology/go-annotation/issues/4866

You can comment on the ticket: https://github.com/geneontology/go-ontology/issues/25682

Thanks, Pascale