Obsoletion notice: GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic (and some descendants)

[ValWood]

Dear all,

The proposal has been made to obsolete

GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic GO:0043928. exonucleolytic catabolism of deadenylated mRNA GO:0034428. nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' GO:0070480 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay

• The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent
• The reason for obsoletion is that the meaning of the term is ambiguous.
• The reason for obsoletion is that this term was an unnecessary grouping term.

Annotations: There are 15 experimental annotations to these terms by (

1 FlyBase 2 GeneDB 1 PomBase 1 SGD 1 TAIR 9 UniProt

There are 2 mappings to this term.

GO:0000291 | hamap2go | HAMAP:MF_03045 > GO:nuclear-transcribed mRNA catabolic process, GO:0000291 | unirule2go | UniRule:UR000187751 > GO:nuclear-transcribed mRNA catabolic process, exonucleolytic

These term is not present in any subset.

Annotations can be viewed here: https://github.com/geneontology/go-annotation/issues/4966

Any comments can be added to the issue: https://github.com/geneontology/go-annotation/issues/4966. Unless objections are received by 14/02/24, we will assume that you agree to this change.

Thanks,

The GO-Ontology Editors

[pgaudet]

@ValWood

Can these terms be replaced by the parent GO:0006402 mRNA catabolic process ?

[ValWood]

They could yes, I will do "replaced by" but mostly people want to use a more specific pathway (i.e NMD, non stop decay, nuclear surveillance etc), these terms group so many things.

I will put the replaced by in the annotation ticket and implement that.