geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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NTR: more 3-demethylubiquinol 3-O-methyltransferase terms #10432

Closed gocentral closed 9 years ago

gocentral commented 11 years ago

Hi,

We currently have a molecular function term for 3-demethylubiquinone-9 3-O-methyltransferase activity (GO:0008689) that looks like it is rat-specific. From this information on the EC number entry, it looks like this enzyme has substrates with varying numbers of prenyl units, depending on species.

http://enzyme.expasy.org/EC/2.1.1.64

The definition that EC uses is generic and would be the equivalent of "3-demethylubiquinone-n 3-O-methyltransferase activity".

Could we have this generic term added as a parent for the existing GO:0008689, and then a cerevisiae specific term added as a sibling (3-demethylubiquinone-6 3-O-methyltransferase activity)? Other organisms probably need other specific function terms, but the only one I know anything about is the S. cerevisiae one!

Thanks,

-Dianna

Reported by: diannafisk

Original Ticket: geneontology/ontology-requests/10232

gocentral commented 11 years ago

Original comment by: ukemi

gocentral commented 11 years ago

Added:

3-demethylubiquinone-n 3-O-methyltransferase activity ; GO:0061542 3-demethylubiquinone-6 3-O-methyltransferase activity ; GO:0061543

Moved EC# to the generic term and rearranged graph accordingly.

Original comment by: ukemi