ukemi
commented
7 years ago [Term] +id: GO:0061819 +name: telomeric DNA-containing double minutes formation +namespace: biological_process +def: "A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:14690602, PMID:2397458] +synonym: "TDMs formation" EXACT [] +is_a: GO:0000722 ! telomere maintenance via recombination +created_by: dph +creation_date: 2016-12-20T09:49:03Z
suggested definition: A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that TDMs are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. TDMs appear as two closely positioned dots in metaphase.
child of: GO:0000722 telomere maintenance via recombination (or suggestion)
PMID: 14690602 PMID: 2397458
GOC:nc GOG:BHF GOC:BHF_telomere