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geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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NTR: intranuclear rod #12937

Closed rjdodson closed 7 years ago

rjdodson commented 7 years ago

Name: intranuclear rod Ontology: cellular_component Synonyms: intranuclear actin rod Definition: Intranuclear rods are aggregates consisting of actin and cofilin that are formed in the nucleus as a consequence of chemical or mechanical stress conditions. The formation of rods is implicated in a variety of pathological conditions, such as certain myopathies and some neurological disorders.

A part_of: nucleus (GO:0044428 nuclear part)

References: PMID:28074884 Actin-Interacting Protein 1 Contributes to Intranuclear Rod Assembly in Dictyostelium discoideum

ukemi commented 7 years ago

Cool! I wonder what they do.

[Term] +id: GO:0061836 +name: intranuclear rod +namespace: cellular_component +def: "A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions." [PMID:28074884] +synonym: "intranuclear actin rod" EXACT [] +is_a: GO:0099512 ! supramolecular fiber