Merge GO:0007098 centrosome cycle and GO:0051297 centrosome organization

[pgaudet]

These two terms have similar definitions and essentially the same children; however GO:0007098 centrosome cycle is a child of GO:0051297 centrosome organization. The former should be merged into the latter.

GO:0051298 centrosome duplication GO:0010457 centriole-centriole cohesion GO:0051299 centrosome separation GO:0007099 centriole replication GO:0061511 centriole elongation

See also https://en.wikipedia.org/wiki/Centrosome_cycle

Thanks, Pascale

[krchristie]

Hi @pgaudet

I'd like to take a look at this before you do anything since centrosomes also cycle into a role as the basal body in ciliated cells, but I won't have time until later in the week when Biocuration is over.

@paolaroncaglia - wanted to alert you to this, though I realize you might not have any bandwidth for ontology stuff right now.

thanks,

Karen

[ValWood]

I don't think merging these terms changes anything. the term used for "spindle pole body cycle" term is "spindle pole body organization" The organization of these macromolecules happens to be sell cycle dependent but this can be accommodated by the definition.

To corroborate, centrosome cycle, is a child of centrosome organization, but these 2 terms have identical children (there is no additional sibling to indicate the need for a separate term)

The equivalent spindle term appears to have been obsoleted back in 2015 http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0030471

[paolaroncaglia]

@krchristie Thanks - as you said, no bandwidth for ontology tickets at the moment I'm afraid.

[krchristie]

I don't have any objection to merging 'centrosome cycle' into 'centrosome organization'.

Thanks for giving me the time to check that this would not affect any of the terms for de novo centriole assembly that occurs when new centrioles are assembled in order to build multiple cilia in a cell.

[pgaudet]

Hello,

The merge is easy but I am unsure about the subclasses. Right now all the steps (centrosome duplication, centrosome separation) are is_a centrosome cycle. I moved all these to 'cell cycle process'. No objections ?

Thanks, Pascale

[ValWood]

Sounds OK...mirrors SPB organization. v

[krchristie]

No objection to having these terms in cell cycle. Even though these centrioles are also sometimes ciliary basal bodies; while cells are cycling in this way, the production of cilia is also coordinated by the cell cycle using basal bodies generated in this way.