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geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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UDP-glucose transmembrane transport into Endoplasmic Reticulum #14450

Closed ValWood closed 7 years ago

ValWood commented 7 years ago

child of GO:0015786 | UDP-glucose transport

standard def

(GO:0015786 can be renamed transmembrane?)

PMID:27587357 Title | THE CONUNDRUM OF UDP-Glc ENTRANCE INTO THE YEAST ER LUMEN.

PMID:27587357

Title | THE CONUNDRUM OF UDP-Glc ENTRANCE INTO THE YEAST ER LUMEN.

UDP-Glc entrance into the endoplasmic reticulum (ER) of eukaryotic cells is a key step in the quality control of glycoprotein folding, a mechanism requiring transfer of a Glc residue from the nucleotide sugar (NS) to glycoprotein folding intermediates by the UDP-Glc:glycoprotein glucosyltransferase (UGGT)........ We conclude that the hut1+ gene product is involved in UDP-Glc entrance into the ER, but that at least another as yet unknown NST displaying an unconventional sequence operates in the yeast secretory pathway.

krchristie commented 7 years ago

@ValWood - So, mostly this is a new term request?

Regarding:

GO:0015786 can be renamed transmembrane?

The definition is not that specific. Perhaps you should direct this to @pgaudet since she's working on transport generally.

pgaudet commented 7 years ago

Hi @krchristie I checked the annotations and it's OK to rename GO:0015786 | UDP-glucose transport -> UDP-glucose transmembrane transport.

The definition should be changed to 'The process in which a UDP-glucose is transported across a lipid bilayer, from one side of a membrane to the other.'

Thanks, Pascale