geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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GO:0004516 (nicotinate phosphoribosyltransferase activity) should now be a ligase? #14684

Closed sjm41 closed 6 years ago

sjm41 commented 6 years ago

GO:0004516 is currently classed as a 'transferase activity' in the GO, with an EC xref of 2.4.2.11

But the EC reclassified this enzyme as a ligase at some point. See: http://enzyme.expasy.org/EC/2.4.2.11

So, please check, but it looks like GO:0004516 should also be moved to be under 'ligase activity' in the GO, with the EC xref updated to 6.3.4.21 (Nicotinate phosphoribosyltransferase).

@hattrill

hdrabkin commented 6 years ago

However, not all known ligases are under 6.3.4, only some of them; I'll change the EC number now, I am at a loss as to why this is now a ligase rather than a transferase; it is not something I would expect to get returned if I searched on "ligase"

hdrabkin commented 6 years ago

EC 6.3: Forming Carbon-Nitrogen bonds GO:0016879 Done