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geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
Creative Commons Attribution 4.0 International
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Rename GO:0000995 'transcription factor activity, core RNA polymerase III binding' to 'RNA polymerase III general initiation factor activity' #15789

Closed pgaudet closed 6 years ago

pgaudet commented 6 years ago

Discussed with @ValWood @RLovering All annotations are to TFIIIA, TFIIIB and TFIIIC, which are general initiation factors.

pgaudet commented 6 years ago

id: GO:0000995 -name: transcription factor activity, core RNA polymerase III binding +name: RNA polymerase III general initiation factor activity namespace: molecular_function -def: "Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well." [GOC:txnOH, PMID:12381659] +def: "An activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC." [GOC:txnOH-2018, PMID:12381659, Wikipedia:RNA_polymerase_III]