suggested definitions for NuRD and Sin3 complex

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Some suggested definitions for NuRD and Sin3 complex terms:

Will add in on Wed May 26th if they're ok.

NuRD complex ; GO:0016581 new exact synonym: nucleosome remodeling and histone deacetylation complex An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in both vertebrates and invertebrates. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.

PMID:10589671 PMID:11743021

Sin3 complex ; GO:0016580 A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins.

PMID:10589671 PMID:11743021 PMID:12865422

and while I'm here:

gurken receptor activity ; GO:0008313 Combining with the ligand Gurken, to initiate a change in cell activity. FB:bf

epidermal growth factor receptor activity ; GO:0005006 Combining with an epidermal growth factor, to initiate a change in cell activity. FB:bf

Becky

Reported by: beckyfoulger

Original Ticket: "geneontology/ontology-requests/1746":https://sourceforge.net/p/geneontology/ontology-requests/1746

[gocentral]

Logged In: YES user_id=482748

Added definitions in as listed above.

Original comment by: beckyfoulger

[gocentral]

• status: open --> closed-accepted

Original comment by: beckyfoulger